Wondering what to watch on Prime Video in September 2025? From exclusive Amazon Originals to top Hollywood blockbusters and international hits, this guide covers all the new TV shows, movies, and must-see content streaming on Prime Video this month.
Whether you’re browsing from the UAE, Saudi Arabia, or anywhere in the MENA region, we’ve rounded up the latest releases to help you find your next favourite binge. Bookmark this page to stay updated on what’s new on Prime Video every week throughout September 2025.
Gen V Season 2 (Series)
Action/Adventure/Sci-Fi | 18+
Starring Jaz Sinclair, Lizze Broadway, and Maddie Phillips, the new season of Gen V premieres exclusively on Prime Video September 17, 2025.
A darkly satirical spin-off of The Boys, Gen V pulls back the curtain on Godolkin University, where young Supes are moulded—and manipulated—by Vought.
In the highly anticipated Season 2, as Homelander tightens his grip on America, a new Dean pushes students toward greater power, while Cate and Sam rise as heroes. Meanwhile, Marie, Jordan, and Emma return burdened by loss, only to uncover a secret program dating back to Godolkin’s origins—one that could change everything.
The Girlfriend Season 1 (Series)
Drama
Starring Robin Wright, Olivia Cooke, and Laurie Davidson, The Girlfriend premieres exclusively on Prime Video September.
Based on Michelle Frances’ bestselling novel, The Girlfriend follows Laura, a woman who appears to have it all: a thriving career, a devoted husband, and her beloved son, Daniel. But her seemingly perfect life starts to unravel when Daniel brings home Cherry, a mysterious new girlfriend. As tensions rise, Laura becomes obsessed with uncovering Cherry’s true intentions—is she a cunning social climber, or is Laura’s paranoia getting the better of her? In this gripping psychological thriller, the truth is never as simple as it seems.
The Runarounds Season 1 (Series)
Drama
Starring Lilah Pate, William Lipton, and Marley Aliah, The Runarounds premieres exclusively on Prime Video September 1, 2025.
The Runarounds follows a group of recent high school grads in Wilmington, North Carolina, who spend the summer chasing an impossible dream: turning their passion for music into stardom. What begins as a simple band experiment quickly becomes a whirlwind of first loves, reckless adventures, and unbreakable bonds that feel like family. With original songs, heartfelt drama, and the exhilarating highs and lows of coming of age, this series captures the raw energy of risking everything at the edge of adulthood to chase your shot at greatness.
Upload Season 4 (Series)
Comedy/Mystery/Sci-Fi
Upload Season 4, starring Robbie Amell, Andy Allo, and Allegra Edwards, premieres exclusively on Prime Video August 25, 2025
Upload is a witty sci-fi comedy about a near-future where death isn’t the end—if you can afford it, you can be ‘uploaded’ to a luxurious digital afterlife. Holographic phones, self-driving cars, AI assistants, and 3D-printed meals make life (and afterlife) more complicated—and hilarious.
In the four-part series finale, a rogue sentient AI threatens to erase Lakeview—and humanity itself. With greedy executives, lingering mysteries, and heartbreak both online and offline, Nathan, Nora, and their friends must team up one last time to save the world.
The Terminal List: Dark Wolf Season 1 (Series)
Action/Thriller | TV-MA
Starring Taylor Kitsch, Tom Hopper, and Dar Salim, The Terminal List: Dark Wolf premieres exclusively on Prime Video August 27, 2025.
Co-created by The Terminal List bestselling author Jack Carr and Season One showrunner David DiGilio, The Terminal List: Dark Wolf is a gripping prequel that traces Ben Edwards’ journey from Navy SEAL to the shadowy world of CIA Special Operations. This high-stakes espionage thriller dives into the darker side of warfare and the human cost of life in the field, with Chris Pratt reprising his role as James Reece.
The Map That Leads to You
Drama/Romance
Starring Madelyn Cline, Josh Lucas, and KJ Apa, The Map That Leads to You premieres exclusively on Prime Video August 20, 2025.
The Map That Leads to You follows Heather, a young woman embarking on one last adventure across Europe with her best friends before settling into her carefully planned life. But when she meets Jack — a magnetic, mysterious stranger — an unexpected spark pulls her into an emotional journey of love, destiny, and self-discovery. As their connection deepens, long-buried secrets and life-altering choices will challenge everything she thought she wanted.
Butterfly Season 1 (Series)
Action/Thriller | TV-MA
Starring Piper Perabo, Daniel Dae Kim, and Reina Hardesty, Butterfly premieres exclusively on Prime Video August 13, 2025.
Butterfly is a gripping spy thriller that weaves high-stakes espionage with tangled family loyalties. David Jung, a brilliant but unpredictable former U.S. intelligence operative hiding in South Korea, sees his quiet life shatter when the fallout from an impossible choice in his past comes back to hunt him. Now hunted by Rebecca —a ruthless young assassin working for the shadowy spy network known as Caddis—David must outwit a deadly game where every move could be his last.
The Pickup
Action/Comedy
Starring Eddie Murphy, Pete Davidson, and Keke Palmer, The Pickup premieres exclusively on Prime Video on 6 August 2025. Buckle up—this ride doesn’t slow down.
The Pickup is a high-octane action-comedy that turns a routine cash run into total mayhem. When two wildly mismatched armoured truck drivers—Russell and Travis —are ambushed by a crew of ruthless criminals led by the cunning Zoe, the job spirals into a chaotic showdown that’s about a lot more than just money. With danger closing in and tempers flaring, this unlikely duo is in for the longest, craziest day of their lives.
The Summer I Turned Pretty Season 3
Drama/Romance | TV-14
The final season of The Summer I Turned Pretty delivers all the love, heartbreak, and unforgettable moments that made the series a sensation. Starring Lola Tung, Christopher Briney, and Gavin Casalegno—don’t miss it, July 16, 2025, only on Prime Video.
As junior year ends, Belly is ready for another dreamy summer in Cousins with her soulmate, Jeremiah. But when unexpected events bring her first love, Conrad, back into the picture, everything she thought she knew is thrown into question. Standing at the edge of adulthood, Belly must finally choose where—and with whom—her heart truly belongs. This summer changes everything.
Ballard Season 1 (series)
Crime | PG13
Ballard stars Maggie Q, Courtney Taylor, and Michael Mosley. Premiering July 9, 2025, only on Prime Video.
From the world of Michael Connelly comes Ballard, a gripping new crime series following Detective Renée Ballard as she takes charge of the LAPD’s underfunded cold case division. With fierce determination and empathy, Ballard reopens the city’s most haunting unsolved crimes—including a serial killer’s trail and a mysterious John Doe—only to uncover a dark conspiracy buried within the force itself.
With a volunteer team and help from retired detective Harry Bosch (Titus Welliver), she faces mounting dangers, personal demons, and the relentless pursuit of justice.